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美国论文代写:纳米载体

美国论文代写:纳米载体

根据Wanyi Tai et al.(2014)的文章,用悬垂药物段和接枝共聚物可以折叠成纳米结构。为了构建一个接枝共聚物,聚合ŷ-camptothecin-glutamate N-car-boxyanhydride几个聚乙二醇网站就完成了。这取决于环开的聚合过程的关键链)(Tai et al., 2014)。在这种情况下,CPT或camptotethecin是一种纯结合的抗癌药物。这种CPT的性质是疏水性的。它是整个折叠过程中的关键动力。当暴露在水中时,就会得到共聚物。Doxorubicin的结果是被折叠成纳米载体,可以单分散用于双药的递送。

美国论文代写:纳米载体
良好的稳定性是由纳米载体描述的,因为他们有合适的PEG外壳设备(Tai et al., 2014)。纳米载体可以通过通过网格蛋白和脂质筏介导的内吞作用通过细胞内的几条细胞系内化,而不存在早产儿的渗漏。这描述了一种更高的CPT的协同作用,以及Dox在几个癌症细胞的方向上(Tai et al., 2014)。这篇文章通过“体内”的研究进一步证实了在肿瘤部位的强性积聚。结果表明,与游离药物相比,异种移植小鼠在异种移植中具有明显的抗肿瘤活性。

美国论文代写:纳米载体

According to the article by Wanyi Tai et al. (2014), folding into nanostructures is possible with pendant drug segments and graft copolymer. In order to construct a graft copolymer, polymerization of ŷ-camptothecin-glutamate N-car-boxyanhydride over several poly ethylene glycol sites is done. This is dependent upon the key chain through the polymerization process of ring open) (Tai et al., 2014). The CPT or the camptotethecin in this situation is an agent of anti-cancer with pure conjugation. The nature of such a CPT is hydrophobic in nature. It serves as the key dynamic force throughout the process of folding. When exposure of this comes in with water, copolymer is gained. Doxorubicin then results in being folded into nano-carriers which can be monodispersed for delivery of dual drug.

美国论文代写:纳米载体
Good stability is depicted by the nano-carriers as they have proper PEG shell equipment (Tai et al., 2014). The nano-carriers could be internalized through several cell lines of cancer through the endocytic pathway mediated through clathrin and lipid raft without the leakage of premature nature. This depicted a higher CPT based synergetic activity as well as Dox in the direction of several cells of cancer (Tai et al., 2014). The article further showed the validation through “in vivo” study exhibiting an accumulation of strong nature within the sites of tumour. It went on to show an activity of anti-cancer prominently in the opposite xenograft with the model of xenograft mice in comparison to free drugs.

 

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